Our world and bodies are becoming increasingly polluted with chemicals capable of interfering with our hormones and thus, possibly, our present and future neural and mental health. As authors Heather Patisaul and Scott Belcher outline, there is a large lack of data and evidence in this causal relationship, which begs a need for further study to accelerate progress in the endocrinology and neuroendocrinology fields. Endocrine Disruptors, Brain, and Behavior focuses on if and how these chemicals, known as endocrine disrupting compounds (EDCs), affect the development and function of the brain and might be contributing to neural disorders rapidly rising in prevalence. The book provides an overall synthesis of the EDC field, including its historical roots, major hypotheses, key findings, and research gaps. The authors explain why even the concept of endocrine disruption is controversial in some circles, how differing definitions of endocrine disruption and what constitutes an "adverse" outcome on the brain shape public policy, and where the current capacity by different stakeholders (industry, academia, regulatory agencies) to evaluate chemicals for safety in a regulatory context begins and ends. The book concludes with suggestions for future research needs and a summary of emerging technology which might prove capable of more effectively evaluating existing and emerging chemicals for endocrine disrupting properties. As such, it provides the context for interdisciplinary and innovative input from a broad spectrum of fields, including those well-schooled in neuroscience, evolutionary biology, brain, behavior, sex differences, and neuroendocrinology.
"“Patisaul and Belcher eloquently depict how the competing desires for a safer, healthier world and 'better living through chemistry' have woven threads of science and policy into a messy tapestry with many scientific holes to be filled and regulatory knots to be untangled. Their descriptions of the complex behaviors of cells, laboratory animals, and humans make it clear that the endocrine system, particularly as it functions through the brain, is critical to optimizing both.>" - Carol Kwiatkowski, PhD, Executive Director of The Endocrine Disruption Exchange (TEDX), and Assistant Professor Adjunct, University of Colorado, Boulder
Формат: Скан PDf
"“Patisaul and Belcher eloquently depict how the competing desires for a safer, healthier world and 'better living through chemistry' have woven threads of science and policy into a messy tapestry with many scientific holes to be filled and regulatory knots to be untangled. Their descriptions of the complex behaviors of cells, laboratory animals, and humans make it clear that the endocrine system, particularly as it functions through the brain, is critical to optimizing both.>" - Carol Kwiatkowski, PhD, Executive Director of The Endocrine Disruption Exchange (TEDX), and Assistant Professor Adjunct, University of Colorado, Boulder
Формат: Скан PDf
https://www.yakaboo.ua/ua/endocrine-disruptors-brain-and-behavior.html